Carrick Therapeutics is a clinical-stage biopharmaceutical company headquartered in Boston, Massachusetts, developing novel oncology therapies aimed at improving outcomes for patients with aggressive and treatment-resistant cancers.
Relay Therapeutics is a Cambridge, Massachusetts clinical-stage precision medicines company (NASDAQ: RLAY) using protein motion to drug historically intractable oncology and genetic-disease targets.
Semnur Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company developing non-opioid pain-management therapies. Its lead program, SP-102 (SEMDEXA), is a novel, non-opioid, preservative-free and particulate-free injectable corticosteroid gel formulation intended to treat moderate-to-severe chronic radicular pain (sciatica).
Chimerix, Inc. was a biopharmaceutical company headquartered in Durham, North Carolina, focused on developing medicines for serious and life-threatening diseases. It is best known for brincidofovir (TEMBEXA), an antiviral approved by the U.S.
Rallybio Corporation (NASDAQ RLYB) is a clinical-stage biotechnology company headquartered in New Haven, Connecticut, founded in 2018, developing and commercializing life-transforming therapies for patients with severe and rare diseases.
Pathios Therapeutics is a clinical-stage oncology and immunology drug discovery and development company based in Oxfordshire, United Kingdom, founded in 2017. The company develops small-molecule inhibitors of the pH-sensing G protein-coupled receptor GPR65 to counteract the immunosuppressive tumor microenvironment; its lead asset PTT-4256 is a…
Solu Therapeutics is a clinical-stage biotechnology company headquartered in Boston, Massachusetts, pioneering a novel class of antibody therapeutics that unlock cell-surface targets by combining small molecules with effector antibodies through proprietary linker technology.
Tenaya Therapeutics is a clinical-stage biotechnology company headquartered in South San Francisco, California, focused on discovering, designing, developing, and delivering potentially curative gene therapies and precision medicines that address the underlying drivers of heart disease.
Areteia Therapeutics was a clinical-stage biotechnology company, formerly based in Chapel Hill, North Carolina, operating in the life-sciences sector. As of the July 2026 enrichment pass the company is no longer operating: areteiatx.com serves only a closure notice directing asset and general inquiries to contact addresses, and the company…
Engrail Therapeutics is a clinical-stage biopharmaceutical company founded in 2019 and focused on precision neuroscience. The company develops innovative, precision-targeted small-molecule therapeutics aimed at the molecular mechanisms and neural circuits underlying nervous system disorders, combining internal discovery with strategic…
Kailera Therapeutics is a clinical-stage biopharmaceutical company focused on the next generation of obesity and cardiometabolic care through a diversified pipeline of GLP-1 based therapies.
Qlaris Bio is a clinical-stage biotechnology company focused on developing first-in-class therapies for ophthalmic diseases, with a mission to preserve vision and prevent blindness. Its lead candidate, QLS-111, uses a novel mechanism of action to lower intraocular pressure by targeting the distal outflow pathway, and is being evaluated for primary…
Connect Biopharma is a clinical-stage biopharmaceutical company headquartered in San Diego, California, dedicated to transforming care for patients with inflammatory diseases such as asthma and COPD.
Ankyra Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, developing "anchored" immunotherapies for cancer and immune-mediated diseases. Its proprietary platform tethers immune-modulating drugs to aluminum hydroxide so that treatment concentrates locally at the disease site, broadening the therapeutic window…
858 Therapeutics is a clinical-stage biotechnology company based in San Diego, California, developing first-in-class and best-in-class small-molecule therapies that target tumor dependencies in DNA damage response (DDR) pathways.
Autobahn Therapeutics is a clinical-stage biopharmaceutical company based in San Diego, California, developing regenerative medicines for central nervous system (CNS) disorders. The company pairs a proprietary brain-targeting chemistry platform - which creates orally administered small-molecule prodrugs designed to cross the blood-brain barrier…
Compass Therapeutics is a clinical-stage biopharmaceutical company developing proprietary antibody-based therapeutics for the treatment of cancer. Its research is grounded in understanding the tumor microenvironment, designing candidates that optimize the components required for an effective anti-tumor immune response and bridge innate and…
Escient Pharmaceuticals is a San Diego, California clinical-stage biopharmaceutical company developing first-in-class, oral small-molecule therapeutics targeting Mas-related G protein-coupled receptors (MRGPRs) along the neurosensory-inflammatory axis.
Trishula Therapeutics is a privately held, clinical-stage immuno-oncology company developing cancer immunotherapies that target immune-evasion mechanisms in the tumor microenvironment.
Vima Therapeutics is a clinical-stage biotechnology company developing novel oral therapies for movement disorders, with a focus on the underlying biology of dystonia and Parkinson's disease.
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