regenerative-medicine

Brain-Referenced In vivo-to-in vitro Developmental Guidance and Evaluation.

Open-source research on the ecological and biochemical mechanisms of regeneration. Models the interaction between Basidiomycete metabolites, mTOR/AMPK/SIRT1 signaling, and TP53/autophagy balance — bridging ecology, computation, and cellular longevity.

A collection of open sourced lectures for Dr. Michael Levin

ARC: Architecture of Regenerative Control. A computational ontology and semi-quantitative scoring framework for comparative regenerative biology.

"Transcriptional Heterogeneity and Cell Cycle Regulation as Central Determinants of Primitive Endoderm Priming" published in eLife (2022)

Research initiative exploring biostasis, cryomedicine and future regenerative technologies.

A dynamical systems model of fibroblast state transitions under pulsed electromagnetic field (PEMF) stimulation, linking migration, matrix production, metabolic activity, and repair-associated functional states.

Literature-based technology assessment of skin substitutes and cultured epithelial autografts for severe burn care.

Mytos is a contract development and manufacturing organization (CDMO) for regenerative medicine and cell therapy. Its iDEM automation platform automates every unit operation of cell culture — coating, seeding, feeding, imaging, passaging and harvesting — in standard 2D T-flask formats, letting clinical-stage biotech companies transfer their manual…

Pelage Pharmaceuticals is a clinical-stage biotechnology company developing regenerative medicines for hair loss based on hair follicle stem cell biology discovered by UCLA researchers.

Allevi is a bioprinting company that designs and manufactures 3D bioprinters, bioinks, and accompanying software for tissue engineering, regenerative medicine, and life-sciences research. Its desktop bioprinters and biomaterials let researchers fabricate living tissue constructs for drug discovery, disease modeling, and organ-on-chip work.

Advanced BioHealing, Inc. was a regenerative medicine company best known for Dermagraft, a cryopreserved human fibroblast-derived dermal substitute used to treat diabetic foot ulcers.

Project Event Horizon: Revolutionary post-transcriptional age reversal research. Develops PT-ARCs — synthetic constructs to reset cellular aging substrates (epigenetic, physical, structural) bypassing Yamanaka factors/OSKM risks. First-principles approach merging quantum biology, topology & non-equilibrium thermodynamics.

XellSmart Biomedical (士泽生物医药) is a clinical-stage biotechnology company based in Suzhou and Shanghai, China, founded in 2021 by Dr. Xiang Li. The company develops clinical-grade, allogeneic, off-the-shelf iPSC-derived cell therapies for central nervous system diseases, with NMPA- and U.S.

Aspect Biosystems is a Vancouver, British Columbia biotechnology company developing Bioprinted Tissue Therapeutics — implantable, allogeneic living tissues designed to replace, repair, or supplement biological function in the body.

Syntax Bio is a synthetic biology company programming the next generation of cell therapies. Its proprietary Cellgorithm platform uses a CRISPR-based system to program and accelerate stem cell differentiation, replacing slow, labor-intensive processes with a rapid, programmable approach that mimics human development to generate diverse functional…

Aspen Neuroscience is a clinical-stage biotechnology company developing personalized regenerative cell therapies for Parkinson's disease. Its lead candidate, ANPD001, is an autologous induced pluripotent stem cell (iPSC)-derived neuron replacement therapy that uses a patient's own cells to restore dopamine function without requiring…

Cellinobio — Cellino Bio develops AI-driven optical bioprocessing technology for personalized regenerative medicine. Its proprietary Nebula platform combines deep learning, laser-based cell management, and closed-loop optical bioprocesses to manufacture patient-specific, induced-pluripotent-stem-cell-derived cell and tissue replacements at scale.

Satellite Bio is a biotechnology company developing off-the-shelf liver cell therapies to treat severe and life-threatening liver diseases. Its tissue therapeutics platform engineers functional hepatocytes designed to engraft and restore liver function, combining the biological power of liver cells with scalable manufacturing and distribution.

A computational pipeline for analyzing tissue regeneration in volumetric muscle loss treatment studies. Enables automated processing of histological and immunohistochemical whole slide images to quantify tissue components, inflammatory responses, and regenerative markers. Provides standardized analysis of spatial tissue heterogeneity.