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gfactor

Laura Cooper, camdu@warwick.ac.uk

ImageJ macros to calculate gfactor and gmap values for cell images

Requires: MorphoLibJ, MultiStackReg, ijl-utilities-wrappers for cellpose

1. RegisterAndConcat

Register the image stacks and concatenate the different stacks to a single hyperstack. Run this before Auto_cellseg.

2. Auto_cellseg

Uses cellpose to automatically segment cells. Need to run this before generateGfacAndGPmaps.

3. generateGfacAndGPmaps

Takes blue and red image stacks and and calculated gfactor and gpmaps. Need to run this before selectRois.

4. selectRois

Allows the users to use the multipoint tool to choose place square ROIs in the cells to measure intensity in blue and red_gfac images and create a table for plotting.

References

Schindelin, J., Arganda-Carreras, I., Frise, E. et al. Fiji: an open-source platform for biological-image analysis. Nat Methods 9, 676–682 (2012). https://doi.org/10.1038/nmeth.2019

P. Thévenaz, U.E. Ruttimann, M. Unser, A Pyramid Approach to Subpixel Registration Based on Intensity, IEEE Transactions on Image Processing, vol. 7, no. 1, pp. 27-41, January 1998.

Stringer, C., Wang, T., Michaelos, M., & Pachitariu, M. (2021). Cellpose: a generalist algorithm for cellular segmentation. Nature methods, 18(1), 100-106.

Stringer, C. & Pachitariu, M. (2024). Cellpose3: one-click image restoration for improved segmentation. bioRxiv.

David Legland, Ignacio Arganda-Carreras, Philippe Andrey, MorphoLibJ: integrated library and plugins for mathematical morphology with ImageJ, Bioinformatics, Volume 32, Issue 22, November 2016, Pages 3532–3534, https://doi.org/10.1093/bioinformatics/btw413

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