Carrick Therapeutics is a clinical-stage biopharmaceutical company headquartered in Boston, Massachusetts, developing novel oncology therapies aimed at improving outcomes for patients with aggressive and treatment-resistant cancers.
Relay Therapeutics is a Cambridge, Massachusetts clinical-stage precision medicines company (NASDAQ: RLAY) using protein motion to drug historically intractable oncology and genetic-disease targets.
Semnur Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company developing non-opioid pain-management therapies. Its lead program, SP-102 (SEMDEXA), is a novel, non-opioid, preservative-free and particulate-free injectable corticosteroid gel formulation intended to treat moderate-to-severe chronic radicular pain (sciatica).
Engrail Therapeutics is a clinical-stage biopharmaceutical company founded in 2019 and focused on precision neuroscience. The company develops innovative, precision-targeted small-molecule therapeutics aimed at the molecular mechanisms and neural circuits underlying nervous system disorders, combining internal discovery with strategic…
Solu Therapeutics is a clinical-stage biotechnology company headquartered in Boston, Massachusetts, pioneering a novel class of antibody therapeutics that unlock cell-surface targets by combining small molecules with effector antibodies through proprietary linker technology.
Alpha-9 Oncology is a clinical-stage radiopharmaceutical company that spun out of the University of British Columbia and BC Cancer in 2019 to develop a portfolio of targeted cancer therapies.
Braveheart Bio is a late clinical-stage biopharmaceutical company developing novel therapeutics for hypertrophic cardiomyopathy (HCM) and related cardiac conditions. Its lead candidate, BHB-1893, is a selective cardiac myosin inhibitor (licensed as HRS-1893 from Hengrui Pharma) designed to reduce excessive heart-muscle contraction and improve…
Rallybio Corporation (NASDAQ RLYB) is a clinical-stage biotechnology company headquartered in New Haven, Connecticut, founded in 2018, developing and commercializing life-transforming therapies for patients with severe and rare diseases.
Chimerix, Inc. was a biopharmaceutical company headquartered in Durham, North Carolina, focused on developing medicines for serious and life-threatening diseases. It is best known for brincidofovir (TEMBEXA), an antiviral approved by the U.S.
Tenaya Therapeutics is a clinical-stage biotechnology company headquartered in South San Francisco, California, focused on discovering, designing, developing, and delivering potentially curative gene therapies and precision medicines that address the underlying drivers of heart disease.
Areteia Therapeutics was a clinical-stage biotechnology company, formerly based in Chapel Hill, North Carolina, operating in the life-sciences sector. As of the July 2026 enrichment pass the company is no longer operating: areteiatx.com serves only a closure notice directing asset and general inquiries to contact addresses, and the company…
Pathios Therapeutics is a clinical-stage oncology and immunology drug discovery and development company based in Oxfordshire, United Kingdom, founded in 2017. The company develops small-molecule inhibitors of the pH-sensing G protein-coupled receptor GPR65 to counteract the immunosuppressive tumor microenvironment; its lead asset PTT-4256 is a…
Link Cell Therapies is a South San Francisco clinical-stage cell therapy company founded by Stanford investigators Robbie Majzner and Crystal Mackall in partnership with Samsara BioCapital, working on the development of safe and effective CAR T agents for patients with solid tumors.
CytomX Therapeutics is a clinical-stage, oncology-focused biopharmaceutical company based in South San Francisco, California, pioneering a novel class of masked, conditionally activated biologic therapeutics built on its proprietary Probody platform.
BlackThorn Therapeutics was a clinical-stage biopharmaceutical company founded in 2015 and headquartered in South San Francisco, focused on discovering and developing targeted therapeutics for brain diseases and central nervous system (CNS) disorders such as major depressive disorder and schizophrenia, using a precision-medicine platform.
Rani Therapeutics is a clinical-stage biotechnology company developing the RaniPill, an ingestible robotic capsule engineered to deliver biologic drugs orally in place of subcutaneous or intravenous injections.
Ray Therapeutics is a clinical-stage biotechnology company developing optogenetic, gene-based medicines to restore vision in people with blinding degenerative retinal diseases. Its approach reprograms surviving retinal neurons to detect light and transmit visual signals to the brain, independent of the underlying gene mutation.
Alpha-9 Oncology is a clinical-stage radiopharmaceutical company developing targeted radioligand therapies and imaging agents to treat solid and hematologic cancers with high precision.
Vima Therapeutics is a clinical-stage biotechnology company developing novel oral therapies for movement disorders, with a focus on the underlying biology of dystonia and Parkinson's disease.
ArriVent BioPharma is a clinical-stage biopharmaceutical company focused on the identification, development, and commercialization of differentiated medicines to address the unmet medical needs of patients with difficult-to-treat diseases, beginning with cancers.
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